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Project

Infant arousal as a predictor of functional outcomes in Down syndrome (DS)

Center:

NC-Carolina Institute for Developmental Disabilities, UCEDD/LEND

Fiscal Year:

2025

Contact Information:

Joseph Piven
[email protected]
919-843-8641

Project Description:

Individuals with Down syndrome (DS) have heterogeneous developmental outcomes and varying support needs which impact quality of life and contribute to significant family stress and financial burden. Identification of objective early markers, with robust neurobiological underpinnings, of specific cognitive, social, and sensory outcomes is key for advancing and tailoring early interventions for DS. This series of testable experiments described in this proposal will yield physiological biometrics of arousal that are objective, present in infancy, and provide clinically actionable targets for treatment in early life to ultimately lead to improved functional outcomes for those with DS.

Keyword(s):

Developmental Disabilities, Children, Adolescents, and Young Adults with Special Health Care Needs

Core Function(s):

Performing Research or Evaluation

Area of Emphasis

Health-Related Activities

Target Audience:

Not Applicable

Unserved or Under-served Populations:

Specific Groups

Primary Target Audience Geographic Descriptor:

Not Applicable