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PASC STUDY (NIH RECOVER: A Multi-site Observational Study of Post-Acute Sequelae of SARS-CoV-2 Infection in Adults)

Contact Information:

Kristy Domnanovich
[email protected]
205-934-1106

Project Description:

This is a combined retrospective and prospective, longitudinal, observational meta-cohort of individuals ages newborn-25 years who will enter the cohort with and without SARS-CoV-2 infection at varying stages before and after infection. Individuals with and without SARS-CoV-2 infection and with or without PASC symptoms will be followed to identify risk factors and occurrence of PASC. This study will recruit participants from inpatient, outpatient, and community-based settings in the United States. Study data including age, demographics, social determinants of health, medical history, vaccination history, details of acute SARS-CoV-2 infection, overall health and physical function, and PASC symptoms will be reported by participants or collected from the electronic health record using a case report form at specified intervals. Biologic specimens will be collected at specified intervals, with some tests performed in local clinical laboratories and others performed by centralized research centers or banked in the Biospecimen Repository. Advanced clinical and radiologic examinations will be performed at local study sites with cross-site standardization.

Core Function(s):

Performing Research or Evaluation, Other Direct/Model Services

Area of Emphasis

Health-Related Activities

Target Audience:

Professionals and Para-Professionals, Family Members/Caregivers, General Public

Unserved or Under-served Populations:

None

Primary Target Audience Geographic Descriptor:

National

COVID-19 Related Data:

Yes