Project Description:
Other research projects include, among others:
Language Development in Neurodevelopmental Disorders. MIND Institute Director Leonard Abbeduto, PhD, and his team are conducting research on language development in children with DD, including fragile X syndrome (FXS), Down syndrome (DS), and autism spectrum disorder (ASD). They have found, as a starting point, that each of these conditions has a unique linguistic signature, with different areas of relative strength and challenge. The biological, behavioral and environmental/family factors that influence the ways in which language develops and the processes that underlie language learning are being examined in individuals with these disorders, with a focus on developing methods for assessment and monitoring treatment efficacy over time. They will continue to examine the efficacy of combining approaches to the treatment of language problems that empower parents to be agents of change and use telehealth technology to decrease the cost and burden and increase the accessibility of treatment.
The RASopathy Clinic and Research Program is under the direction of Katherine Rauen, MD, PhD, who joined the MIND and CEDD faculty in 2014. The NF/Ras Pathway Genetics Clinic provides comprehensive medical management for patients with RASopathies: neurofibromatosis 1 and 2, Noonan syndrome, capillary malformation-AV malformation, Costello syndrome, cardio-facio-cutaneous syndrome, Legius syndrome, schwannomatosis or any RASopathy-like condition. The RASopathy Research Program is a collaborative consortium of investigators led by Dr. Rauen studying the association of ASD in the RASopathies, how germline Ras/MAPK pathway dysregulation affects organ system development, and how germline Ras/MAPK pathway affects functional interactions among glia and neurons in the brain to impact development.
Target Audience:
Students/Trainees (long or intermediate trainees), Community Trainees / Short term trainees, Professionals and Para-Professionals, Family Members/Caregivers, Adults with Disabilities, Children/Adolescents with Disabilities/SHCN, Legislators/Policy Makers, General Public
Primary Target Audience Geographic Descriptor:
State, National, International
