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Product

Journal: Altered Gut-Brain Communication in Neurodevelopmental Disorders.

Center:

CA-UC Davis at the MIND Institute, UCEDD/LEND

Fiscal Year:

2026

Contact Information:

Jill Silverman
[email protected]
916-734-8531

Product Description:

Angelman Syndrome mice have evidence of constipation, likely mediated by altered UBE3A+ enteric nerves. Supplementation with Tb could restore GI physiology, and locomotor activity, but this benefit was potentially not due to restoration of the gut microbiome. These findings provide insight into potential future therapeutic targets through the MGB axis for AS patients.

Keyword(s):

Product/Publication Type(s):

Peer-reviewed publications in scholarly journals Published/In Press

Target Audience:

Professionals

Alternative Format:

To Obtain Copies (URL or Email):

https://doi.org/10.1111/nmo.70109

COVID-19 Related Data:

N/A

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Mailing address:
PO Box 8787
Silver Spring, MD 20907-8787