Sputum Tobramycin Concentrations in Cystic Fibrosis Patients with Repeated Administration of Inhaled Tobramycin.
Product Description:
No evidence of significant drug accumulation in respiratory secretions with repeat dosing of TSI was seen. Peak bioactive concentrations, although lower than peak total concentrations, were still generally well within the bactericidal range. Sputum induction as a method for determining airway drug concentrations appears safe and feasible.
Keyword(s):
cystic fibrosis, inhaled tobramycin
Product/Publication Type(s):
Peer-reviewed publications in scholarly journals submitted
Target Audience:
Professionals
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COVID-19 Related Data:
N/A