Cellular Imaging Core

Children's Hospital Intellectual and Developmental Disabilities Research Center

Center URL: https://iddrc.org/
Core URL: http://www.iddrc.org/cores/cellular-imaging/

Core Personnel
Core Director: Chinfei Chen, MD, PhD
Core Assistant Director: Anthony Hill, PhD

Core Description

The Cellular Imaging Core offers fee-based access to specialized hardware and software for confocal imaging, scientific visualization, and image analysis. The objective of the Cellular Imaging Core is to provide affordable access to state-of-the-art equipment, services, training and advice for projects using microscopy and image analysis techniques.

Services

Microscopy

High quality digital microscopy with a wide range of objectives (1X - 100X)
Quantitative, high-resolution imaging of molecular architecture and cellular ultrastructure
Multi-label fluorescence imaging that allows intracellular localization and co-localization of large number of antigens (up to 10).
Awake behaving Multiphoton Microscopy
In vivo and live cell imaging over hours to days
High temporal resolution time-lapse imaging using confocal microscopy
Advanced microscopy methods including FRAP, FRET
Quantitative calcium (as well as other cations such as magnesium and zinc) imaging with the confocal microscopes
Optogenetics
Tiling and Stitching
On-site Consultation