Developmental Mechanisms of Human Structural Birth Defects (P01)

Submission Date: September 25, 2007

The size and duration of each award will vary

The purpose of this Program Announcement is to support innovative, multidisciplinary, interactive, and synergistic program projects that integrate basic, translational, and clinical approaches to understanding the developmental biology and genetic basis of congenital human malformations. Each Program Project application must consist of at least three component projects. At least one project must be clinical or translational in nature. The component projects must share a common central theme, focus, or objective on a specific developmental defect or malformation that is genotypically, mechanistically, biologically, or phenotypically analogous or homologous in both animal models and humans. Any non-mammalian or mammalian animal model may be used, as long as it contributes to the common overall theme or objective of the program project.

For more information, please visit the NIH grants webpage.