Parkinson's Disease Biomarker Program (PDBP) Discovery Projects (U01)

Submission Date: September 4, 2014

Award Ceiling: $490,000

The purpose of this funding opportunity announcement (FOA) is to support up to three years of study for the discovery, assay optimization, and replication stages required for the development of biological biomarkers for Parkinsons disease (PD).It is expected that studies funded under this FOA will integrate with and enhance the NINDS Parkinson's Disease Biomarker Program (PDBP). Discovery or pilot projects may use samples from either the PDBP or otherextant biospecimens and data, as long as consent for the extant biospecimens and data enables deposition of all data into the PDBP Data Management Resource (DMR). It is expected that the replication stage study will use PDBP biospecimens and data. This FOA is only for studies related to human biomarkers; animal or other disease model studies are not appropriate for this FOA. A timeline including milestones is required for all studies. Annual milestones will provide clear indicators of a project's continued success or emergent difficulties and will be used to evaluate the application not only in peer review but also in consideration of the awarded project for funding of non-competing award years.

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