Randi Hagerman, MD

Center for Excellence in Developmental Disabilities at the UC Davis MIND Institute
UC Davis Health System
2825 50th Street
Sacramento, CA 95817
Phone: 916-703-0247
Email: rjhagerman@ucdavis.edu
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Last Updated: August 22, 2017

Randi Hagerman

Leadership: Associate UCEDD Director
Primary Activity Coordinators: Research Director
Project/Program/Clinic Contacts: Fragile X Research Programs
Discipline(s): Medicine-Pediatrics
Medicine-Developmental-Behavioral Pediatrics
AUCD Council Membership: No Council Membership
Research: Dr. Hagerman has more than 20 years of experience in the field of neurodevelopmental disorders and fragile X syndrome - the most common inherited cause of mental retardation. Her research focuses on the correlation between an individual's molecular genotype, or genetic make-up, and their physical and behavioral characteristics. She also has a strong clinical and research interest in autism and has conducted research examining the association between autism and fragile X syndrome. Her most recent books, Neurodevelopmental Disorders: Diagnosis and Treatment, and Fragile X Syndrome: Diagnosis, Treatment, and Research, 3rd Edition, were published, respectively, by Oxford University Press in 1999 and Johns Hopkins University Press in 2002.
Education: B.A. University of California, Davis, Davis, California, 1971
M.D. Stanford University School of Medicine, Palo Alto, California, 1975
Service: Advisory Board of the Fragile X Association of Northern California
Scientific Council of L'Association Mosaiques (Paris)
Advisory Board of the Los Angeles Fragile X Association
Editorial Board of Mental Health Aspects of Developmental Disabilities
Fellow of the International Association for the Scientific Study of Intellectual Disabilities
Member of the Leadership Committee of the M.I.N.D. Institute
Member of the Committee for Pediatric Research - UC Davis
Council Member of Western Society of Pediatric Research
Governing Council,Society for the Scientific Study of Behavioral Phenotypes (SSBP, England)
Member of SSBP
Editorial Board of the Journal of Developmental and Behavioral Pediatrics
FAS Task Force of Santa Clara Advisory Board


Dr. Randi Hagerman is a developmental and behavioral pediatrician and the Medical Director of the MIND Institute at UC Davis. She is internationally recognized as both a clinician and researcher in the fragile X field. Dr. Hagerman received her M.D. from Stanford University where she also carried out her Pediatric residency. She completed a Fellowship in Learning and Disabilities and Ambulatory Pediatrics at UC San Diego and, subsequently, spent the next 20 years from 1980 to 2000 at the University of Colorado where she headed Developmental and Behavioral Pediatrics. She co-founded the National Fragile X Foundation in 1984 in Colorado and developed a world-renowned fragile X research and treatment center. In 2000, Professor Hagerman moved to UC Davis to be the Medical Director of the MIND Institute. Dr. Hagerman and her team discovered the Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) which is a neurological disorder that affects older male and rare female carriers of fragile X. Dr. Hagerman's research involves genotype-phenotype correlations in fragile X and she carries out this research in collaboration with her husband, Paul Hagerman, M.D., Ph.D. Professor Randi Hagerman has written over 200 peer-reviewed articles and numerous book chapters on neurodevelopmental disorders. She has written several books on fragile X including a 3rd Edition of Fragile X Syndrome: Diagnosis, Treatment, and Research which was published in 2002 by Johns Hopkins University Press. Dr. Hagerman has received numerous awards for her research in fragile X syndrome including the Jerrett Cole Award from the National Fragile X Foundation for unselfish dedication to work with fragile X children and adults, the Bonfils-Stanton Foundation Award for Science including Medicine, the IASSID Distinguished Achievement Award for Scientific Literature, the 2005 Distinguished Scholarly Public Service Award from UC Davis, and the 2006 Dean's Award for Outstanding Mentoring at UC Davis. In 2004, to honor both Randi and Paul Hagerman in recognition of their work in FXTAS, the National Fragile X Foundation established the Hagerman Award. This award recognizes research accomplishments in the field of FXTAS and is given at the bi-annual International Conference on Fragile X. In 2008, the National Fragile X Foundation again honored Dr. Hagerman with a Lifetime Achievement Award. Dr. Hagerman has worked internationally to establish fragile X clinical programs and research programs throughout the world. Dr Hagerman is currently carrying out multiple targeted treatment trials in FXS and in autism including a controlled trial of Arbaclofen, minocycline, ganaxolone, mGluR5 antagonists developed by Roche and another by Novartis, and sertraline. She is also the PI of a controlled trial of memantine in older fragile X premutation carriers with FXTAS.