Molecular Genetics

Children's Hospital Intellectual and Developmental Disabilities Research Center
Molecular Genetics

Center URL:
Core URL:

Core Personnel
Core Director: Louis Kunkel, PhD
Core Assistant Director: Catherine Brownstein, PhD

Core Description

The overall objective of the Molecular Genetics Core is to provide a central location where IDDRC investigators can have access to high quality, low cost genomic technology services and expertise in a timely, affordable manner. These services can be broken down into six main functional components: 1) Sequencing (Next generation and Sanger); 2) High-Throughput SNP Genotyping, 3) qPCR, and digital detection PCR (ddPCR); 4) Microarray Analysis; and 5) Sample and Data Management and Analysis, and 6) Microsatellite Genotyping



Services Provided Include the Following:

  • Next-Gen Sequencing
  • DNA Sequencing
  • High-Throughput SNP, qPCR, and ddPCR
  • Microarray Analysis
  • Microsatellite Genotyping
  • Genomic Data Management


Major instrumentation in the Molecular Genetics Core includes:

  • Two Applied Biosystems 3730 DNA Analyzer
  • Hamilton Microlab STARPlus Automated Workstation. 
  • Affymetrix Gene Chip Scanner 3000 with Autoloader
  • Qiagen Autopure System
  • Fluidigm Biomark System
  • Bio-Rad ddPCR QX200
  • Agilent Bioanalyzer
  • Qiagen Qiacube
  • Illumina Beadstation 500GX Genetic Analysis System


Last Edited: 12/27/16 12:00 AM by Theresa Trapilo