Genetics Core
Kennedy Krieger Institute Intellectual and Developmental Disabilities Research CenterCenter URL: https://www.kennedykrieger.org/research-training/centers-labs-cores/intellectual-developmental-disabilities-research-center
Core URL: https://www.kennedykrieger.org/research-training/centers-labs-cores/intellectual-developmental-disabilities-research-center/genetics-core-objectives
Core Personnel
Core Director: David Valle, M.D.
Core Co-Director: Denise Batista, Ph.D.
Core Keywords
Centralized tissue culture; amino acid analyses; organic acid analyses; molecular cytogenetics; cytogenetic analysis; karyotyping; genomic abnormalities; current-generation sequencing; molecular genetics; bioinformatics
The Genetics Core supports research focused on the role genetic factors play in atypical physical, cognitive, and behavioral development. Supported research focuses on etiology, natural history, and prognosis of a variety of conditions associated with developmental delay, neuropsychiatric disorders affecting children, and behavioral and physical features of developmental disabilities. The services provided by the Genetics Core include:
- Cell line establishment and tissue culture
- Cytogenetic analysis, namely karyotype and fluorescence in situ hybridization
- Single nucleotide polymorphism microarray
- Identification of regions with genomic homozygosity and parent of origin for genomic abnormalities
The Core also serves as an interface for IDDRC-supported projects with the resources of other Genetics Core facilities established within the Johns Hopkins Medical Institutions, including current-generation sequencing.
Last Edited: 06/10/17 12:00 AM by Corina Miclea