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Biostatistics and Bioinformatics

Children's Hospital of Philadelphia, University of Pennsylvania
Biostatistics and Bioinformatics

Center URL: http://www.research.chop.edu/programs/iddrc/
Core URL: http://www.research.chop.edu/programs/iddrc/studydesigncore.php

Core Personnel
Core Director: Mary Putt, Ph.D.
Core Associate Director: Peter White, PhD

Core Keywords
Biostatistics and Bioinformatics

Core Description

The Biostatistics and Bioinformatics Core supports IDDRC researchers in experimental design and biostatistical analysis of data from traditional sources, as well as studies that use genomic and functional genomic data.

Objectives

  • Support the needs of the IDDRC investigators in the areas of experimental design, biostatistical and statistical genetics analysis, and bioinformatics
  • Offer unique individualized educational opportunities for core users that leverage and complement existing educational programs at University of Pennsylvania
  • Engage in the development of new methods needed to address issues in data analysis that are raised by core users


Services

Study Design

  • Evaluate feasibility and validity of proposed designs
  • Calculate sample size and statistical power and precision
  • Advise on the development of appropriate data collection tools
  • Support design of new research proposals

Data Analysis

  • Provide brief consultations on statistical analyses and on presentation of analyses
  • Develop data and analysis workflows for projects requiring significant data integration
  • Collaborate fully on the analysis of data
  • Integration of genomic and functional genomic data with clinical and public data
  • Develop graphs and tables to summarize results for presentation and publication
  • Develop new statistical and informatics methods to address issues raised by users' research 

Education

  • Raise awareness of training in biostatistical and bioinformatics methods available through the university
  • Provide education in statistical and bioinformatics methods for Center members
  • Work one-on-one with investigators to reinforce and build on existing levels of expertise


Last Edited: 01/14/11 12:00 AM by Oksana Klimova