Dr. Kuo is an Associate Professor of Internal Medicine, Pediatrics, Psychiatry and Biobehavioral Sciences in the David Geffen School of Medicine at UCLA, and of Health Policy and Management in the UCLA Fielding School of Public Health. She is a Co-Director of the Health Care Transitions Research Network (HCT-RN), an MCHB-funded network for key stakeholders in the field to connect, collaborate, promote research, and develop innovative projects that will increase understanding of the factors at the person, family, community, health system, and policy levels that influence population-level measures of life course outcomes.

Clinically, Dr. Kuo directs the UCLA Medicine-Pediatrics Comprehensive Care Center, a 365- day a year primary care office with extended hours and services. She is the Director of the Research Training and Education Core of the NICHD-funded P50 Center for Autism Research and Treatment (CART) at UCLA, as well as a primary care consultant at the UCLA Child and Adult Neurodevelopmental (CAN) Clinic. Her clinical focus has been youth and young adults with ASD and she is building a registry of these individuals at UCLA.

Dr. Kuo has also been extensively involved in the teaching of public health and is the Director of the Pathways for Students into Health Professions program, an MCHB-funded Pipeline program. She is also the Director of Training for the NHLBI-funded P50 Center for Population Health and Health Disparities. Her work in Maternal and Child Health has led to the publication of a book, Child Health: a Population Perspective, published by Oxford University Press in 2015.

Dr. Kuo is the Chair of the Transition Care Committee of the Medicine-Pediatrics Program Directors Association and has spearheaded a national effort to develop and pilot a health care transition curriculum for primary care residents. She is a member of the Academic Pediatric Association's Health Care Transition and Disease Self-Management Special Interest Group and is also on the Task Force for Adults with Chronic Conditions Originating in Childhood in the Society for General Internal Medicine. Most recently, she is on the Steering Committee for Pediatric to Adult Care Transitions Workgroup led by the Council of Subspecialty Societies of the American College of Physicians, working to raise awareness among internists about the care for adults with ASD and intellectual disabilities.