Genetic Factors in Birth Defects
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Department of Health and Human Services National Institutes of Health National Institute of Child Health and Human Development Title: Genetic Factors in Birth Defects Contract RFP #: RFP-NIH-NICHD-2006-02 URL: http://www.fbo.gov/spg/HHS/NIH/NICHD/RFP%2DNIH%2DNICHD%2D2006%2D02/listing.html Submittal Date: April 24, 2006 Number of Awards Anticipated: 1 Amount Available: The final contract will contain the price/cost provisions agreed upon by the Government and the Offeror. The Pediatric Epidemiology Section (PES) of the Epidemiology Branch (EB), an intramural research group within the Division of Epidemiology, Statistics and Prevention Research (DESPR) of the National Institute of Child Health and Human Development (NICHD), conducts research on identifying risk factors for abnormal childhood development. An area of particular interest is the genetic contribution to birth defects. The PES conducts much of its research via contracts, collaborating scientifically with the Contractors. The NICHD intends to contract with an institution to acquire from a large population in a defined geographical area (e.g. births within a given state): 1) already collected samples containing DNA from a large number of children who have major birth defects and medical documentation sufficient to describe the birth defects; 2) already collected samples containing DNA from normal control children; 3) any and all existing data currently in the possession of the resultant Contractor on factors that may influence pregnancy outcome and birth defects. Additionally, as a contract option the NICHD is looking to obtain for the children who have major birth defects and for the normal control children: 1) maternal serum, plasma, amniotic fluid or other biological samples obtained during the pregnancy that produced the affected or normal control child; 2) samples containing DNA from the mothers; 3) samples containing DNA from the fathers, where maternal samples containing DNA are present. Last Edited: 03/14/06 02:09 PM by Evette Mezger |
