Genetics Core

Kennedy Krieger Institute Intellectual and Developmental Disabilities Research Center
Center URL: https://www.kennedykrieger.org/research-training/centers-labs-cores/intellectual-developmental-disabilities-research-center
Core URL: https://www.kennedykrieger.org/research-training/centers-labs-cores/intellectual-developmental-disabilities-research-center/genetics-core-objectives

Core Personnel
Core Director: David Valle, M.D.
Core Co-Director: Denise Batista, Ph.D.

Core Keywords
Centralized tissue culture; amino acid analyses; organic acid analyses; molecular cytogenetics; cytogenetic analysis; karyotyping; genomic abnormalities; current-generation sequencing; molecular genetics; bioinformatics

The Genetics Core supports research focused on the role genetic factors play in atypical physical, cognitive, and behavioral development. Supported research focuses on etiology, natural history, and prognosis of a variety of conditions associated with developmental delay, neuropsychiatric disorders affecting children, and behavioral and physical features of developmental disabilities. The services provided by the Genetics Core include:

• Cell line establishment and tissue culture
• Cytogenetic analysis, namely karyotype and fluorescence in situ hybridization
• Single nucleotide polymorphism microarray
• Identification of regions with genomic homozygosity and parent of origin for genomic abnormalities

The Core also serves as an interface for IDDRC-supported projects with the resources of other Genetics Core facilities established within the Johns Hopkins Medical Institutions, including current-generation sequencing.

 

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Last Edited: 06/10/17 12:00 AM by Corina Miclea