Intellectual and Developmental Disabilities (IDD) Models Core

Waisman Center
Intellectual and Developmental Disabilities (IDD) Models Core

Center URL: http://www.waisman.wisc.edu/
Core URL: http://www.waisman.wisc.edu/cores-idd-models.htm

Core Personnel
Core Director: John Svaren, Ph.D.
Core Co-Director: Anita Bhattacharyya, Ph.D.
Core Co-Director: Qiang Chang, Ph.D.
Core Co-Director: Su-Chun Zhang, M.D., Ph.D.
Core Co-Director: Xinyu Zhao, Ph.D.

Core Description

The Intellectual and Developmental Disabilities (IDD) Models Core in the Waisman Center provides a number of resources to investigators within our center as well as to other campus investigators. First, the core provides mouse models of human conditions, along with behavioral testing capabilities to characterize these models and test new therapies. Second, we provide state-of-the-art stem cell technologies to support creation of induced pluripotent stem cell lines for IDD conditions as well as specialized genome editing services. Finally, we provide high quality, cost effective, microscopy technology and expertise for characterization of both stem cell and mouse models of IDD conditions.



Services

Cellular Imaging and Analysis Lab

  • Fluorescence/Brightfield and Confocal Microscopy
  • Fluorescence Quantitation
  • Cellular Imaging and Analysis Instrumentation
  • Consultation, Support and Training
Induced Pluripotent Stem Cells (iPSC) Services
  • iPSC cloning, including mycoplasma testing, marker immunofluorescence, and WiCell characterization (for University of Wisconsin researchers)
  • Gene mutation correction/induction
  • Endogenous site reporter insertion
  • Safe harbor site reporter insertion
  • Lineage-tracing dual insertion
  • Custom gene editing projects
Rodent Models
  • Reproductive services
  • Transfers & shipments
  • Behavioral testing
  • Transgenic/knockout services
  • Technical consultation




Last Edited: 05/04/17 12:00 AM by Oksana Klimova